GLOBAL TB CAUCUS STATEMENT ON THE GLOBAL FUND EIGHTH REPLENISHMENT

The Global TB Caucus welcomes the commitments announced during the Global Fund Eighth Replenishment. With US $11.34 billion already pledged, the Replenishment has shown that global solidarity remains possible even in a challenging economic climate. 

The Results Report 2025 makes clear why these commitments matter. In 2024, 7.4 million people with TB were treated, 25.6 million people accessed HIV treatment, and 162 million mosquito nets were delivered. These results show the value of sustained investment and country leadership in protecting communities and strengthening health systems. 

The replenishment result reflects the changing realities of global health financing. While some donors are still to finalize their pledge, it is already clear that less funds available for Grant Cycle 8 compared to Grant Cycle 7. Most countries will receive reduced allocations. Those with greater economic capacity or lower disease burden will see the sharpest reductions.  

This underlines the critical importance of domestic resource mobilization and strengthening national leadership to protect HIV, TB and Malaria outcomes,  ensure that essential services remain uninterrupted and expedite access to innovations.

Lord Herbert of South Downs, Chair of the Global TB Caucus, said: 

“Given the current economic challenges many countries are facing, the Global Fund’s successful replenishment is a powerful affirmation of the importance of its work. These commitments will save lives and help countries deploy better tools faster. We must build on this momentum. TB cannot remain the world’s most neglected epidemic. Political leadership and sustained investment are essential if we are to protect communities and secure a future where no one dies from a preventable and curable disease.” 

The Eighth Replenishment comes at a moment when countries face tighter budgets, rising health needs and growing pressure on national systems. TB remains one of the world’s deadliest infectious diseases, killing an estimated 1.23 million people in 2024. Without Global Fund support to national health programmes, these figures would be much higher. Since 2002, the partnership has saved 70 million lives and continues to strengthen systems that protect against future health threats. 

The Global TB Caucus urges all governments to sustain and increase their commitments in the coming months, whether this be through domestic resource mobilization or additional support to the Global Fund. The Eighth Replenishment has set a strong foundation, but more is needed to keep momentum and meet the ambitions outlined by countries themselves. 

Continued political will and investment from every government will determine whether we accelerate toward ending TB or face a costly reversal. The Global TB Caucus stands ready to support leaders to turn pledges into sustained impact for communities.